Divergent synaptic dynamics originate parallel pathways for computation and behavior in an olfactory circuit

Fly navigational responses to odor motion and gradient cues are tuned to plume statistics

Non-genetic adaptation by collective migration

* co-first authors

Microscopic phage adsorption assay: High-throughput quantification of virus particle attachment to host bacterial cells

Bifurcation enhances temporal information encoding in the olfactory periphery

* contributed equally; # co-corresponding authors

Physics of bacterial chemotaxis

E. coli do not count single molecules

* contributed equally; ǂ contributed equally; # co-corresponding author

Lattice ultrasensitivity produces large gain in E. coli chemosensing

co-corresponding author

Olfactory cues and memories in animal navigation

Signal integration and adaptive sensory diversity tuning in Escherichia coli chemotaxis

Extracting spatial information from temporal odor patterns: insights from insects

Temporal novelty detection and multiple timescale integration drive Drosophila orientation dynamics in temporally diverse olfactory environments

* contributed equally

Optimal inference of molecular interaction dynamics in FRET microscopy

Direct measurement of dynamic attractant gradients reveals breakdown of the Patlak-Keller-Segel chemotaxis model

* contributed equall

Odour motion sensing enhances complex plume navigation

* co-corresponding authors

• News and Views: Flies catch wind of where smells come from, by Floris van Breugel and Bingni W. Brunton, Nature, 10.1038/d41586-022-03561-3, Nov 9 2022
• Yale News article by Bill Hathaway
• YouTube: Flies smell the motion of odors and use it to navigate
• How animals follow their nose, Knowable Magazine, by Dana Mackenzie, March 6 2023

Sensing complementary temporal features of odor signals enhances navigation of diverse turbulent plumes

* contributed equall

Navigation: Where is that smell coming from?

Collective behavior and non-genetic inheritance allow bacterial populations to adapt to changing environments

Escherichia coli chemotaxis is information limited

* contributed equally, #co-corresponding authors

• Неоптимальная обработка информации замедлила хемотаксис кишечной палочки
• Bacterial bandwidth, Yale News
• Information processing constrains how E. coli bacteria navigate chemical gradients
• E. coli’s Streaming Bandwidth

A Primed Subpopulation of Bacteria Enables Rapid Expression of the Type 3 Secretion System in Pseudomonas aeruginosa

Non-Genetic Diversity in Chemosensing and Chemotactic Behavior

Walking Drosophila navigate complex plumes using stochastic decisions biased by the timing of odor encounters

* contributed equally

• Olfactory Navigation: Tempo is the key by Celani, eLife
• How insects find their targets in a chaotic world by William Hathaway
• YouTube video
• Yale scientists track how walking fruit flies navigate to odor sources by Katlin Flores

Adaptive tuning of cell sensory diversity without changes in gene expression

* corresponding authors

• Dynamic risk management in cell populations
• Cellular bet hedgers cash in when environment changes

Controlling and measuring dynamic odorant stimuli in the laboratory

Front-end Weber-Fechner gain control enhances the fidelity of combinatorial odor coding

Organization of Embryonic Morphogenesis via Mechanical Information

A rule from bacteria to balance growth and expansion

Modulation of flagellar rotation in surface-attached bacteria: a circuit for rapid surface-sensing

Spatial Self-Organization Resolves Conflicts Between Individuality and Collective Migration

* contributed equally

• Bacterial balancing act: preserving diversity while on the move
• Spatial Self-Organization Resolves Conflicts Between Individuality and Collective Migration

Behavioral variability and phenotypic variability in bacterial chemotaxis

Olfactory receptor neurons use gain control and complementary kinetics to encode intermittent odorant stimuli

* contributed equally; 1corresponding authors

Feedback between motion and sensation provides nonlinear boost in run-and-tumble navigation

• Movie

Phenotypic diversity and temporal variability in a bacterial signaling network revealed by single-cell FRET

Patterned Disordered Cell Motion Ensures Vertebral Column Symmetry

* corresponding authors

Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators

* contributed equally

Presynaptic GABA receptors mediate temporal contrast enhancement in Drosophila olfactory sensory neurons and modulate odor-driven behavioral kinetics

Direct correlation between motile behavior and protein abundance in single cells

Non‐genetic diversity modulates population performance

* contributed equally

• Stochastic gene expression: bacterial elites in chemotaxis
• Recommended in F1000Prime

Trade-offs in Bacterial Chemotaxis and the Adaptation of Non-Genetic Diversity

Adaptability of non-genetic diversity in bacterial chemotaxis

Limits of feedback control in bacterial chemotaxis

Note: There were several typos in the published PDF. Make sure to use our corrected version

Intensity invariant dynamics and odor-specific latencies in olfactory receptor neuron response

Functional diversity among sensory receptors in a Drosophila olfactory circuit

Regulated tissue fluidity steers zebrafish body elongation

Cell-Fibronectin interactions propel vertebrate trunk elongation via tissue mechanics

Adaptation dynamics in densely clustered chemoreceptors

Systems Immunology: a primer for Biophysicists

Edited by Edward Egelman

Stochastic coordination of multiple actuators reduces latency and improves chemotactic response in bacteria

Modeling cellular signaling: taking space into the computation

The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub

High-throughput, subpixel precision analysis of bacterial morphogenesis and intracellular spatio-temporal dynamics

* Co-corresponding authors

• Movies

Temporal coding of odor mixtures in an olfactory receptor neuron.,

Fine-Tuning of Chemotactic Response in E. coli Determined by High-Throughput Capillary Assay,

Guidelines for visualizing and annotating rule-based models

Thermal robustness: lessons from bacterial chemotaxis

Efficient modeling, simulation and coarse-graining of biological complexity with NFsim,

• Supp Video 1
• Supp Video 2
• New approaches to modeling complex biochemistry, Nature Methods

The processivity of peptidoglycan synthesis provides a built-in mechanism for the robustness of straight-rod cell morphology,

Spatial organization of the flow of genetic information in bacteria,

Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response,

* Co-first author

Interdependence of behavioural variability and response to small stimuli in bacteria,

RodZ, a component of the bacterial core morphogenic apparatus,

Understanding Modularity in Molecular Networks Requires Dynamics

* Co-corresponding author

Minimally invasive determination of mRNA concentration in single living bacteria,

• Supp. Doc
• Supp. PPT

Relationship between cellular response and behavioral variability in bacterial chemotaxis

* Corresponding author

Hidden stochastic nature of a single bacterial motor

Dynamical determinants of inducible gene expression in a single bacterium

Simulations of magneto-convection in the solar photosphere - Equations, methods, and results of the MURaM code,

AgentCell: a digital single-cell assay for bacterial chemotaxis

* Corresponding author

Real-time RNA profiling within a single bacterium

From molecular noise to behavioral variability in a single bacterium

* co-first author

Polarization of photospheric lines from turbulent dynamo simulations

On the interaction between convection and magnetic fields,

The zigzag path of buoyant magnetic tubes and the generation of vorticity along their periphery

Small-scale photospheric fields: Observational evidence and numerical simulations

The physics of twisted magnetic tubes rising in a stratified medium: Two-dimensional results

Equilibrium of twisted horizontal magnetic flux tubes

MHS-equilibrium of twisted magnetic tubes

The rise of twisted magnetic tubes in a stratified medium